Yes. If the operations are physically taking place in SC, then you would need to file a return for SC.
Then since you are a resident (I am assuming since it is registered in IL) you will need to file the IL return to report your income as ALL income from ALL sources must be reported on your resident return.
When filing you will need to complete your non-resident state first and then your resident state claiming a credit on your resident state for taxes paid to your non-resident state.
Multiple States
File Non Resident State Return
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