We don’t know the reasons you might not be able to efile an amended return from the Desktop program. It might depend on why you are amending. Like you can’t efile to change the Filing Status.
It might need to know that the original return was efiled and Accepted. You first need to check the filing status inside the program so it knows it was filed and accepted. Open your return and go up to the top black menu bar first item
File > Electronic Filing > Check Electronic Filing Status
Then save your return and close it. Close the program and reopen it.
You may need to update the program first. I saw a post that said the Desktop status issue was fixed so it shows accepted now. Go to menu Online- Check for updates.
