It depends.
If your employer removed the correct amount of HSA contributions from Wages in boxes 1, 3, and 5 on your W-2 the first time around, then the answer would be "no" about amending the PA return (i.e. if the only change was the code W amount).
However, if your employer entered the wrong code W amount the first time around on the W-2, then the employer is likely to have removed the wrong amount from Wages in boxes 1, 3, and 5 on your W-2 the first time around. If you see that the Wages amount in box 1 has changed on the W-2C, then you will probably need to amend your PA return as well, since it is likely that the amount of tax in PA will change.
Note, you can't tell how much your employer removed from Wages in boxes 1, 3, and 5 by looking at your W-2; you have to ask your employer what they did.
