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I think some details are important.

If the loss is a personal  loss, then the loss is not deductible for Federal taxes. 

However, it may be deductible on your state taxes.  Don't take this next statement as gospel, but here is a site that explains it could be deductible in CA:  https://www.caltax.com/forums/topic/virtual-currency-scam/  You should check with your state to determine if it is deductible on your state taxes.

 

If your loss is not a personal loss, rather a loss by a business, the situation may be different.  I personally don't know how that would be handled.