Yes. You should continue to file a joint return disclosing her income and tax information from Switzerland.
You elected to treat your spouse as a resident when you filed joint returns for 2019 and 2020. The choice to be treated as a U.S. resident for federal income tax applies to all later years and she will have to file a separate return, in case you decide to file separately.
The election to treat a spouse as a resident for tax purposes can be ended by revocation of choice by either of you. You can not make the choice again later once you revoke.
You may also have to file form 8938 and FBAR if required.
For more information click on the link below.
Filing Tax Return if my spouse is nonresident
Tax Residency
FBAR
8938
