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hard to know for sure...the Actual MO 2020 instructions say on page 2:

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If your form has a 2-D barcode, mail your return to the Department of Revenue address as indicated below:

 

Refund returns: P.O. Box 3222, Jefferson City, MO 65105-3222

 

Balance due returns: P.O. Box 3370, Jefferson City, MO 65105-3370

 

Refund returns claiming a property tax credit: P.O. Box 3385, Jefferson City, MO 65105-3385

 

Balance due returns claiming a property tax credit: P.O. Box 3395, Jefferson City, MO 65105-3395

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(  https://dor.mo.gov/forms/MO-1040%20Instructions_2020.pdf  )

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For the manually-entered paper forms...without a 2D bar code, it is:

 

Refund or no balance due:  Missouri DOR,  PO box 500, Jefferson City, MO 65105-0500

 

Balance Due:  Missouri DOR,  PO box 329, Jefferson City, MO 65105-0329

 

____________*Answers are correct to the best of my knowledge when posted, but should not be considered to be legal or official tax advice.*