I save my TurboTax return (file) in a Taxes folder that I created on my laptop so it's not saved within the TurboTax program. (Open your return in TurboTax and choose Save As and select the folder location that you prefer.) I have been saving like this for so long that I don't remember if TurboTax creates a folder separately from the program for their default location.
Some people have had success by just temporarily turning off their virus protection and then updating successfully without having to uninstall.
