I just ran updates on my Mac today and was able to reopen TurboTax from the Applications folder with no problem.
See this help article for troubleshooting steps for Mac issues.
If you confirmed that you have all of the minimum system requirements, you might also try clearing your cache and cookies.
If after trying all of the options mentioned you still have the same problem:
See this help article for instructions on how to contact TurboTax customer support depending on which product you are using.
@steven_in_oc
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