If you reported on your prior year tax returns the home office depreciation, it must be recaptured when the home is sold. So you need to indicate in the program that you must report the sale.
If you are using the TurboTax online editions then you must use the Premium edition which supports Schedule D and Form 8949 for capital gains, whereas the Deluxe online edition does not support this.
If you are using the TurboTax desktop editions installed on a personal computer then any of the editions can be used.
