Get your taxes done using TurboTax

It is income.  It doesn't matter what you do with it except if you roll it over to another 401K or IRA account.   It will add to your income and may push you inter a higher tax bracket so be careful.  And there is a 10% Early Withdrawal Penalty if you are under 59 1/2.  But you can avoid the 10% penalty if you use money from a IRA instead of a 401K to buy a new house.