It depends. Does she have any income? Since you are married typically, and usually the best option, you would file a joint return that covers both of you even if she has no income.
You could however file as "Married Filing Separately" and if she has no income she would not need to file a return. However, that could result in a higher tax for you. Click here for more information on filing jointly or separately.
Generally, if your combined gross income is below $25,900 if you are both under age 65, below $27,300 if one of you is over age 65, or $28,700 if you are both over age 65 you would not need to file a tax return.
Click here to review Publication 501 paying attention to the sections titled "Who must file" and "Filing Status."
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