Tax on OT - filing

What is the difference of filling married-jointly or married-seperatley with the following scenario;

 

One works 80 plus hours a week.

 

On payroll - makes 160k/year.

 

The other owns a business and makes 75k/year.

 

Which is the best way to file; married - jointly or married-seperatley for the best tax on OT benefits?