[Event] Ask the Experts: Investments: Stocks, Crypto, & More

Thank you for taking the time to answer my question.  I am filing my 1040ES in August before I make or take the IRA withdrawals.  Do I just assume that I am making the withdrawals from the IRA and estimate this $5800 tax you estimated and when I would I submit the payments?   Or the taxes are withheld when I make the withdrawals from the Schwab IRA the last two months of the year?