If you didn't report your self employment expenses on your 2020 tax return, you would need to amend your 2020 tax return to include those expenses. You are not allowed to report expenses that were paid in 2020 on your 2021 tax return.
You may be able to claim a Business Use of Home on Form 8829 for the room you used for your business. There are two methods to determine the expense -- simplified and actual expense. Here are some links with details on how to calculate the expense:
Home Office Deduction
IRS Business Use of Home
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