Hello & good Morning!!
1st question: Yes, you can either pay estimated taxes on your side gig separately or you can increase your withholdings with your employer.
2nd question: Yes you can claim as an expense all the tools & materials used for your You Tube gig.
TurboTax article for common business deductions: https://turbotax.intuit.com/tax-tips/small-business-taxes/taking-business-tax-deductions/L5RueYPVS
https://ttlc.intuit.com/turbotax-support/en-us/help-article/self-employed/write-business-expense/L8d...
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