Personal LLC and W-2 Spouse

My wife is a therapist and owns her own PLLC. I am a salaried W-2 employee. I added her expected income in for my withholdings when I completed my paperwork with my employer and they asked if there was more than 1 job for the household. My company takes out extra withholdings based on the combined income. Does my wife still need to file estimated quarterly tax payments?