Does 401k withdrawals affect Medicare premiums at 65.

1. Husband wants to withdraw about 780,000$ from his traditional 401k to buy a  home this year in 2022. I will be 65 in Sept 2023 , he will be 65 in Feb. 2024. Will this this high income affect Medicare premiums when it comes time for us to apply? 
2. if yes, how.?
I heard Medicare reviews  tax returns from 2 years back to determine premiums.