There are a few ways to reduce tax exposure on RMDs. Some of the suggestions though would be very dependent on your age and other investment strategies. For example: converting your savings into a Roth IRS that doesn't require RMD means that your money can stay growing tax free or left to heirs, but this option has to be done before a certain age.
If you are still working and have a 401K, you could continue to work past 72 and not have to take distributions on the 401k (Again very dependent on your situation).
One good option is if you have to take RMD you could donate the RMD to a qualified charity under the QCD rule (doesn't apply to 401k). This rule lets you contribute up to $100,000 directly to charity so that you don't have to pay taxes on that amount. It is a good way to give and save on taxes. (Money donated this way can't be deducted on taxes as charitable contribution).
Really having a comprehensive financial plan could help you to prepare for RMDs. Talking to a good financial planner before you are required to take RMDs would be a great way to develop a strategy that is right for you.
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