That's really not a tax question and depends a great deal on your particular situation and also on whether you think it makes sense to sell some part of your holdings now just in order to realize the gains so they can be offset by those realized losses.
The IRS allows you to match up your gains and losses for any given year to determine your "net" capital gain or loss. If you end up with a net loss, you can use up to $3,000 per year to reduce your taxable income. Any additional losses can be carried-forward into future years, to offset either capital gains or another $3,000 in ordinary income. Whether or not this is worthwhile for you I couldn't say.
You also have to take account of the fact that you'll be selling assets that you may wish to hold longer term.
Answers are correct to the best of my ability but do not constitute legal or tax advice.
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