No, it does not appear that you need to amend your 2021 return because you reported the Roth over-contribution before the due date for your 2021 return. Moreover, it appears that you reported the over-contribution correctly and properly accounted for the fact that you had a small loss in connection with the over-contribution. As long as all of this was reported timely, that is before the due date for your 2021 return, then you can ignore the 1099-R that you received in early 2022.
@SteveKoz
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