Yes, this is still relevant for the 2021 tax year. The IRS has not changed the instructions for reporting options, so you are likely to be blocked from e-filing your tax return if you enter a negative number for proceeds.
The IRS Schedule D instructions describe how to report options sales.
As @ColleenD3 paraphrased, "The take away is that gains from expired options are reported with the gain amount in the proceeds column and no amount in the cost basis column, while losses from expired options are reported with the loss amount in the cost basis column and no amount in the proceeds column."
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