Yes.
If you sell your investment/rental properties at a profit, the capital gains are included as income for the determination of your premium credit.
Please read this document from Healcare.gov for more information.
Please note that the premium credit is reduced to 0 when your income exceeds 400% of the Federal poverty levels.
However for tax years 2021 and 2022, the American Rescue Plan of 2021 (ARPA) temporarily expanded eligibility for the premium tax credit by eliminating the rule that a taxpayer is not allowed a premium tax credit if his or her households income is above 400% of the Federal Poverty Line.
@Daisy1301 I have edited my answer.
[Edited 02/08/22 | 7:30AM PST]
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