Yes. You can add the expenses of sale to possibly create a loss on Schedule D.
The back of the Form 1099-S states:
To determine if you have to report the sale or exchange of your main home on your tax return, see the Instructions for Schedule D (Form 1040). If the real estate was not your main home, report the transaction on Form 4797, Form 6252, and/or the Schedule D for the appropriate income tax form.
