BrianVW,
If the 1099-S is for the sale of a home, then I find that if I go to Forms view and select Schedule D, there is a Quick Zoom button to a Home Sale Worksheet. If you are using Step-by-Step, you might find
https://ttlc.intuit.com/community/entering-importing/help/where-do-i-enter-form-1099-s/00/26218
of value in navigating to the relevant portion of Desktop Premier. It did work on my TT Premier Desktop copy updated this morning.
