No, not on Schedule E.
Home office may only be reported on Schedule C or Schedule F.
According to the IRS:
"Self-Employed Persons
If you use your home in your trade or business and file Schedule C (Form 1040 or 1040-SR), report the entire deduction for business use of your home on line 30 of Schedule C (Form 1040 or 1040-SR). Whether you need to complete and attach Form 8829 to your return depends on how you figure your deduction. See Line 30 in the Instructions for Schedule C for more information.
If you use your home in your farming business and file Schedule F (Form 1040 or 1040-SR), report your entire deduction for business use of the home on line 32 of Schedule F (Form 1040 or 1040-SR). Enter “Business Use of Home” on the dotted line beside the entry."
IRS Pub 587
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