Sold a primary home I lived in for 4 years bought in 2009, but rented out the last 2.5 years. Does it still qualify for exception from the gains?

I have made a large gain. Your instructions within Turbo say no and it says yes???
Did You Use This Home for Anything Other Than Your Primary Home? But the note for this question say to answer no if use for reasons other than primary??????
  Can you clarify?