There is a screen in the rental section that asks if you lived in the home and allows you to take the exclusion. There is also a screen in the sale of main home that allows you to enter your depreciation. What matters is whether it was rented in the year you are doing taxes. If you say it was not rented in the program, you will not be able to enter the rental section at all. Keep track of your depreciation should you need to enter it manually.
