Investors & landlords

Yes, you can use TurboTax Deluxe to prepare Form 6781.  

Here's how:

1.  Enter "Form 6781" in the Search box located in the upper right of the program screen, and press enter. 
2. Choose the "Jump to Form 6781" link.
3. TurboTax will ask if you have "any straddles or Section 1256 contracts?" Answer "yes".
4. Then, proceed through the interview and answer the questions as they apply to your situation.

Here's some more information you may find helpful: What is Form 6781: Gains and Losses from Section 1256 Contracts and Straddles