No, but you could take a portion of your mortgage interest and real estate taxes as part of your home office expenses.
Homeowners may deduct a portion of both real estate taxes and qualified mortgage interest (but not principal) payments on the home. Because mortgage interest and real estate taxes are deductible without regard to the home office deduction, the real advantage of the home office deduction for homeowners is that it converts an itemized deduction into a far more tax-advantaged business expense deduction. Homeowners can also claim a depreciation deduction to recover some of the home's purchase price.
