Yes, you may.
This, from IRS Publication 526:
"Generally, you can deduct contributions of money or property you make to, or for the use of, a qualified organization. A contribution is “for the use of” a qualified organization when it is held in a legally enforceable trust for the qualified organization or in a similar legal arrangement."
The afghans are for the use of a qualified organization. Make sure that you get the home's tax identification number for your records.
