An amount in Box 10 on a W-2 would not create tax on the income but it could limit the credit for expenses you entered.
So if the program first computed a credit for Child and Dependent care expenses. but then you entered an amount in Box 10, the expenses the program assumed you paid out-of-pocket (and applied towards a credit) are eliminated by the "tax-free" assistance reported in Box 10.
In this case, the credit is lowered or eliminated, resulting in a higher tax liability than when the credit was first applied (without that amount in Box 10).
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