If the office was inside of your home, in a bedroom for instance, then a portion of the gain on sale of the house does not need to be allocated to the office. You treat the sale as if you never had a home office. If the office is detached from the house, then you need to allocate a portion of the home sale to the office and recapture the deprecation taken on the office to the extent you have a gain on sale of the house.
You should report the sale of the house in TurboTax to make sure it qualfies for special tax treatment with regard to the $250,000 or $500,000 exemption on sale or your primary residence.
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