Yes, shipping costs to ship resale items to buyers are a business expenses. If the item sells for $50, for example, and shipping cost is $5, you would report $55 in revenue (amount paid to you by customer) then report $5 to 'Shipping Costs' on your Schedule C.
Your Ebay/Poshmark fees are also an expense. You can enter them under 'Other Common Business Expenses' as 'Commissions'.
Here's more info on Business Income and Expenses.
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