Deductions & credits

"If I annualize the first quarter by multiplying by 4, it exceeds the SALT cap."

irrelevant

 

"I had to make a Q4 2021 estimate payment in January 2022. Combined with my Q1 2022 W-2 withholding,"

why are you considering these amount.?

Line 4 is itemized deductions for the period. That's all.