Yes, you can generally always use the standard deduction, unless a specific circumstance prohibits it.
AGI doesn't change standard deduction v. itemized (unless you get into high income areas.) What matters is filing status, (single/MFJ/MFS/Head of household) and age.
For single under age 65, the standard deduction is $12,550. Unless you have other itemized deductions that together with the $4,000 to charities would be over $12,550, use the standard.
https://www.irs.gov/pub/irs-pdf/i1040gi.pdf
https://www.irs.gov/pub/irs-pdf/f1040.pdf look in box for line 12a
**Disclaimer: Effort has been made to offer correct information; but due to the discussion forum limitations, the poster disclaims any legal responsibility for the accuracy of the poster's response**
