Maybe. If your cost basis was the same as the selling price, then yes, you will have neither a gain nor loss (this assumes no commission or fees were charged). However, and to follow-up on the comments from @AmyC, your exercise price is going to be your cost basis if the sale is a qualifying disposition. A qualifying disposition for ISOs is when you sell 2 years after the grant date and more than 1 year after the exercise date.
In contrast, a disqualifying disposition is anything other than a qualifying disposition. With a disqualifying disposition you pay ordinary tax on compensation income and long term or short term gain on capital gains.
For ISOs, compensation income is the spread when ISOs are sold for a profit. The ISO cost basis is the cost at exercise for the shares plus any amount included in compensation income from a disqualifying disposition.
@pr0
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