Generally, you are advised to not amend your return if you qualify for the unemployment exclusion. However, if excluding unemployment make you eligible for additional federal credits and deductions not already included on the original tax return, then you should amend your return.
For example, the IRS can adjust returns for those taxpayers who claimed the Earned Income Tax Credit (EITC) and, because the exclusion changed the income level, may now be eligible for an increase in the EITC amount which may result in a larger refund. However, taxpayers would have to file an amended return if they did not originally claim the EITC or other credits but now are eligible because the exclusion changed their income.
You can read the IRS article here.
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