It may not be necessary for you to make estimated tax payments in this scenario.
According to the General Rule in the IRS's Publication 505, Tax Withholding and Estimated Tax,
In most cases, you must pay estimated tax for 2021 if both of the following apply.
1. You expect to owe at least $1,000 in tax for 2021 after subtracting your withholding and tax credits.
2. You expect your withholding and tax credits to be less than the smaller of:
a. 90% of the tax to be shown on your 2021 tax return, or
b. 100% of the tax shown on your 2020 tax return. Your 2020 tax return must cover all 12 months.
[Bolding is mine.]
I should point out that, in 2.b, the relevant percentage is 110% if less than two-thirds of your gross income for 2020 and 2021 is from farming or fishing, and your 2020 adjusted gross income was more than $150,000 ($75,000 if your filing status for 2021 is married filing a separate return. See the ** beneath Figure 2-A, Do You Have To Pay Estimated Tax? in the link above.
However, as pointed out in the excellent Post by TurboTax CHAMP Hal_Al,
If your goal is only to avoid the underpayment penalty, then paying 100% of the prior year tax liability is the “safe haven”. So, even if you make a third quarter payment, it doesn't have to be for the full amount. Increasing your withholding at work is a better option.
I'm assuming you're aware of the potential for an exclusion from income of the gain on the sale of a home. If not, please see Do I have to pay taxes on the profit I made selling my home? in the TurboTax article Tax Aspects of Home Ownership: Selling a Home.
