Property/state/local taxes are capped at $10,000. Preschool is only deductible if it is so that you can work or go to school yourself. You can deduct home mortgage interest on the first $750,000 ($375,000 if married filing separately) of indebtedness. However, higher limitations ($1 million ($500,000 if married filing separately)) apply if you are deducting mortgage interest from indebtedness incurred before December 16, 2017.
More generally, your itemized deductions can only lower your income to zero. If the Standard deduction already does that, itemized ones are of no benefit.
