Since you are required to depreciate business property, be it SCH E and/or SCH C, yes you should be taking depreciation on the SCH E for the 25% of your primary residence that is classified as rental property, and depreciation on SCH C for the percentage of space classified as a home office for your SCH C business.
I can't resist mentioning though, that 10% for a home office seems rather large to me. Maybe you include in that space used for storing product you sell in your SCH C business, and that would justify such a large percentage for the home office then. Either that, or you have a really tiny house, which would not be at all unusual.
Now one thing you want to make sure of, is that your percentages are correct. As an example, if your house is 1000 square feet and you rent out 250 square feet, then 25% of your property is SCH E rental property use. Then if 100 square feet is used for a home office for your SCH C business, that would be 100 sq feet out of the total 1000 square feet, or 10%. It would "NOT" be 100 sq feet out of the 750 square feet not being rented.
