No.
If you are a regular W-2 employee, you are no longer (effective 2018) allowed to deduct job expenses, including a home office. Even when you were allowed to, it was only an itemized deduction subject to the 2% of AGI threshold.
The (up to) $250 educator expense adjustment to income ("above the line" deduction) still applies. See https://www.irs.gov/newsroom/what-teachers-should-know-about-deducting-out-of-pocket-classroom-expen....
