It depends, if you are writing off the Home Office on a Schedule C business, or you are taking the deduction as part of Employee Business Expenses.
Writing off the Home Office for a personal business will give you a greater deduction for tax purposes, than as an Employee Business Expense.
Since Employee Business Expenses are no longer deductible on the Federal, then you need to see about the advantage it may give you on your State return.
@graytrone
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