The IRS only allows you to deduct the cost of diapers if you are doing so to relieve the effects of a particular disease. There is no requirement for having a written prescription. If the doctor has recommended the diapers for a disease that has caused her incontinence, then this out-of-pocket expense is deductible. Please view this IRS link for more information.
Note: You will need to itemize deductions to claim medical expenses.
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