When do you pay taxes when selling shares from ISO grant?

I received ISO options in the past. (granted more than 2 years from now)

I exercised the ISO options in the past (exercised more than 1 year from now)

When I exercised, I did the AMT calculation and I did not owe anything.

Today, I am selling the shares from the ISO options. From what I understood, I will simply pay capital gains on the gain of the sale.

When do I pay taxes on the sale? 

Do I need to make a payment to the IRS now or at the end of the year when I calculate my overall taxes?