After you file

yes but you must let the joint return be fully processed. 

 

while it's possible you entered something incorrectly in the MFS return having a larger tax bill when using this filing status is common.   certain credits are lost and certain retirement contributions are restricted.  you would also expect to see a large increase if your spouse had very little income  and the standard deduction was used

 

examples

filing joint

H - 50K income  s-10K income total 60K

std deduction say $28k (rounded) 

taxable 32K

tax 3400

filing MFS

H - 50K

std deduction $14K

taxable $36K

tax 4100

 

you would need to compare line by line the joint and your mfs returns to see what's happening.