Estimated Tax Payments

I was hoping to perform a Roth conversion in Q4 and I want to avoid a penalty for under tax payment.  My situation is that I will not be able to rely on Safe Harbor as I had a much larger tax liability last year and will not get near the 110% payments of last years liability.  Can I make a large estimated tax payment for Q4 to cover this liability.  How much additional work will be needed when I am filing my 2023 taxes (I think it requires breakout on form 2210?)  Thanks