Yes. Either the on-line version or the version you buy at a store.

With on-line you can complete your return and then pay for the service (unlike buying at a store and then using the software). Then you can file on-line in the TurboTax software...follow the instructions. I imagine the version that runs locally on your computer works the same way.

@samjclem87 We can't do it for you, but you can select the option to e-file (instead of printing and mailing) when you near the end of preparing your return.  If you've completed your tax return, when you sign back in, do the following:

1. Select File in the left menu (expand your browser window if you don't see this, or select the menu icon in the top left corner).
2. On the Just one more step screen, follow steps 1 and 2 if you haven't already.
3. Select the Start button to the right of Step 3.
4. On the Let's get ready to e-file screen, select I want to e-file.
5. Follow the instructions to e-file your return.

Reference:  How do I change from mail to e-file in TurboTax Online?