No. Once submitted, it is not possible to cancel the submission. You must wait until you get an accept or reject from the IRS and that will occur 24 to 48 hours after the IRS begins to process returns on Jan 23. Before then, do absolutely nothing to your return. If the IRS rejects your return, then make the necessary corrections and resubmit. It the IRS accepts your return then you will have to prepare an amended return and file it by mail.
