Hello,
It is not clear whether you excluded the gain from the sale of your home in 2021, because if you did, that would disqualify you from excluding the gain on the sale of your home in 2022.
I have attached links that cover the rules for claiming the exemption below, which you may find informative:
https://turbotax.intuit.com/tax-tips/home-ownership/tax-aspects-of-home-ownership-selling-a-home/L6t...
https://www.irs.gov/taxtopics/tc701
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