Hello....this is what I encountered.
I was experiencing the same problems with having TurboTax give notice (on my new 2021 iMac desktop) that the tax return for the year I was preparing was UNSAVED, then unable to save because it was locked. I did a GET INFO and it was not locked and I had full read/write authority.... THIS ended up being the problem for me: I was accessing the tax return file of preparation from a THUMB drive. Once I moved the tax return file (in this case xxxx.tax2021) to my desktop (back onto my physical iMac the problem ceased to exist and I could continue in peace!!!
Todd
